Throughout his criminal career, Vito Genovese was involved in several significant deals, takeovers, and key projects that further solidified his position as a top mob boss. He orchestrated various illegal operations, including racketeering, extortion, and drug trafficking, amassing considerable wealth and power in the process. Genovese was known for his fierce leadership style and the loyalty he inspired among his associates, making him a force to be reckoned with in the criminal underworld.