In 2019, Meyers declared for the NFL draft and signed with the New England Patriots as an undrafted free agent. He spent two seasons with the Patriots, where he showed promise as a reliable target for quarterback Cam Newton and earned the trust of the coaching staff. In his rookie season, Meyers caught 26 passes for 359 yards and 0 touchdowns. In his second season, he improved his stats, finishing with 59 receptions for 729 yards and 0 touchdowns.